Tranexamic acid

Tranexamic acid is one of the most effective skin-brightening and anti-pigmentation actives used in modern dermatology and cosmetic formulations. Originally developed as a hemostatic (anti-bleeding) drug, it was later discovered to significantly reduce melasma, dark spots, and post-inflammatory hyperpigmentation (PIH) — making it a top choice for achieving bright, even-toned, and healthy skin.
INCI Name: Tranexamic Acid
Appearance: White crystalline powder
Solubility: Freely soluble in water; limited solubility in ethanol
pH Stability: Stable between 5.0–7.0
Heat Stability: Good; avoid prolonged heating above 60 °C
Key Cosmetic & Dermatological Functions

1. Skin Brightening / Anti-pigmentation: Inhibits plasmin activity, reducing melanocyte stimulation caused by UV and inflammation. Helps fade melasma, sunspots, and acne marks.

2. Anti-inflammatory: Soothes redness and irritation from UV exposure or acne.

3. Barrier Support: Improves overall skin tone uniformity and resilience.

4. Synergistic Effects: Works effectively with niacinamide, glutathione, and vitamin C derivatives for enhanced brightening results.
   Common Applications
   Brightening serums and toners
   Melasma treatment creams
   Post-acne hyperpigmentation correctors
   Soothing and recovery skincare products
   Formulation Guidelines
   Typical Use Level: 2–5% (commonly 3%)
   Solubility: Water soluble
   Add Phase: Cool-down phase (<50 °C)
   pH Range: 5.0–7.0 (best around 5.5–6.0)
   Compatibility: Works well with niacinamide, glutathione, panthenol, allantoin, and hyaluronic acid
   Avoid Combining With: Strong acids (e.g., glycolic, lactic) or very low pH systems (<4.5)
   Stability Tips: Store in opaque packaging; can be stabilized with antioxidants such as ascorbyl palmitate
   Safety Profile
   Non-irritating, non-sensitizing, and safe for long-term use. Suitable for sensitive and post-inflammatory skin. Dermatologically approved for daily use in cosmetic concentrations.